Because the yellowing caused by hepatitis B is due to damage to liver cells caused by the hepatitis B virus, the uptake, binding and excretion of bilirubin by the liver is impaired and jaundice caused by the accumulation of bilirubin in the blood, complications associated with heavy hepatitis and severe hyperbilirubinemia may lead to bilirubin encephalopathy, which can be life-threatening. In such cases, the treatment needs to take two methods: 1, for hepatitis B for the cause of treatment, the application of nucleoside analogues for antiviral treatment. 2, through liver protection treatment to promote liver function recovery, some patients can also be jaundice to reduce yellowing treatment, the clinical often applied anti-yellowing drugs are phenobarbital, ursodeoxycholic acid, magnesium sulfate solution and gardenia yellow oral solution.