The unconscious shaking of the thumb may be seen in the following cases: 1, Parkinson’s disease: mainly seen in older people over 60 years of age, is a degenerative disease of the nervous system, manifested as tremors of the limbs, bradykinesia, abnormal muscle tone, abnormal posture and gait, some patients can appear the phenomenon of unconscious shaking of the thumb. 2, idiopathic tremor: is a cause of unknown, mainly tremor of the nervous system diseases, patients do not have increased muscle tone and bradykinesia. 3, extrapyramidal diseases: mainly seen in some cerebrovascular diseases, as well as tumors, encephalitis, etc., the sequelae of extrapyramidal diseases. 3.Extrapyramidal diseases: mainly seen in cerebrovascular diseases, tumors, encephalitis, etc. The sequelae of extrapyramidal diseases are involuntary movements and involuntary trembling of the thumb.