Whether a platelet count of 396 x 10^9/L is serious depends on the cause of the rise in platelet count. If the rise in platelet count is caused by dehydration, infection and other factors, it can be decreased after the original disease is controlled and is usually not serious; if the rise in platelet count is caused by chronic granulocytic leukemia and other factors, it is more serious.
1. Dehydration: when the human body in heat stroke, acute gastroenteritis or other causes of severe vomiting, dehydration occurs, platelets due to blood concentration can be a transient rise, can reach 396 × 10 ^ 9 / L. At this time, we must actively hydrate, correct electrolyte disorders, platelets can fall. Active treatment is generally not serious.
2. Infection: when there is infection in the body, such as pneumonia, acute enteritis, myositis, etc. can lead to a transient rise in platelets, platelets can also reach 396×10^9/L. At this time, active anti-infection treatment (cephalosporin, etc.), after the primary disease is under control, platelets will return to normal, and it is generally not serious.
3. Chronic granulocytic leukemia: it can lead to a rise in platelets, and at the same time bleeding, anemia and other symptoms may occur. Treatment should be directed at chronic granulocytic leukemia. TKI inhibitors such as imatinib or dasatinib may be given.
Platelet count of 396 x 10^9/L, there may be other causes, such as primary thrombocythemia, it is recommended to seek medical attention, find the cause, and treat the cause under the guidance of the physician.