Whether or not liver disease is contagious is related to the specific type of liver disease and cannot be generalized. Liver disease includes a wide range of diseases. Alcoholic hepatitis, drug-related hepatitis, steatohepatitis, and autoimmune hepatitis cause liver damage, but are not contagious. Viral hepatitis, such as hepatitis A, hepatitis B, hepatitis C, hepatitis D, and hepatitis E, all result from viral infections and are contagious. Among them, hepatitis B and C can be transmitted through blood, mother-to-child and sexual contact, such as transmission from mother to baby during delivery or in utero during pregnancy, as well as transmission by medical injection and blood products; hepatitis A and E are mostly transmitted through fecal-oral route, such as transmission due to accidental ingestion of food and water contaminated by hepatitis patients’ stools. For infectious liver disease, we must control the transmission route, pay attention to personal hygiene, choose a light diet, prohibit smoking and alcohol, prohibit spicy and greasy, regular rest and rest, prohibit staying up late, moderate exercise, and keep a happy mood.