Menopause should refer to menopause, which is a normal physiological process for women and is a normal aging of the ovaries. For some women there may be no obvious effects, but other women may show obvious symptoms of perimenopause, such as hot flashes, sweating, irritability, agitation, poor night sleep, which obviously affects the quality of life, followed by corresponding complications of the cardiovascular system such as atherosclerosis, hypertension, coronary heart disease, etc., followed by obvious calcium loss, and even Alzheimer’s disease etc. If the above-mentioned conditions manifest themselves more adequately, the corresponding hormone replacement therapy needs to be given, and estrogen and progestin replacement therapy can be given in cases where there are no obvious contraindications. If the uterus has been removed, a single estrogen replacement therapy can be given.