Sleep deprivation hand numbness, should promptly consult a doctor to identify the cause, may be diabetic peripheral neuropathy, cerebrovascular disease, vertebral artery cervical spondylosis, cerebral ischemia, etc., need to be under the guidance of the doctor to carry out targeted treatment, such as drug therapy. 1. Diabetic peripheral neuropathy: sleep deprivation hand numbness may also be caused by diabetic peripheral neuropathy, because diabetic peripheral neuropathy can easily lead to distal limb nerve damage, triggering a variety of discomforts, the common main numbness of the limbs, acidity, etc., can be used for methylcobalamin tablets, sodium prostaglandin tablets. 2. Cerebrovascular disease: cerebrovascular disease can also lead to sleep deprivation hand numbness symptoms, such as stroke, mainly because of cerebrovascular disease can easily lead to cerebral arterial stenosis or occlusion, followed by ischemia, resulting in discomfort. Aspirin, clopidogrel bisulfate tablets, atorvastatin, etc. can be used. 3. Neurogenic cervical spondylosis: some patients with symptoms of sleep deprivation and hand numbness may be related to neurogenic cervical spondylosis, because the herniated intervertebral disc compresses the nerve root, causing hand numbness. Drugs such as eperisone hydrochloride tablets can be used, and surgery can be performed if necessary. However, it can not be ruled out is caused by other factors, it is recommended that the patient timely consultation to identify the cause of the disease, by the doctor to clarify the cause of the disease, to give targeted treatment.