Colorectal cancer generally refers to colorectal cancer, which is a common malignant tumor in the gastrointestinal tract, formed by abnormal gene regulation of normal colorectal tissues under the stimulation of carcinogens and abnormal proliferation of normal mucosa. Colorectal cancer is relatively common among human GI tumors. The pathogenesis of colorectal cancer is still unclear, and some studies have shown that the occurrence of colorectal cancer is related to poor dietary habits, such as high-fat diet, which stimulates the intestine to produce carcinogens through a series of chemical reactions; high-fiber diet helps the transmission and elimination of intestinal contents, reducing the stimulation of intestinal carcinogens to the intestine, and low-fiber diet leads to the increase of colorectal cancer incidence. Early colorectal cancer symptoms are not obvious and are generally easy to be ignored. With the progress of tumor, rectal cancer can show rectal irritation symptoms, which can be manifested as diarrhea, urgency and heaviness, and incomplete stool. The symptoms of colon cancer are closely related to the tumor site: the symptoms of right hemicolectomy are mainly unexplained anemia, weakness, loss of appetite, emaciation, dyspepsia, fever and other symptoms, and occasionally abdominal vague pain; the left hemicolectomy is mainly manifested by change of stool habit, sometimes there may be symptoms of blood in stool, progressive constipation and difficulty in defecation in advanced stage, and more likely to have intestinal obstruction. The progression of colorectal cancer includes local infiltrative growth, and it can also metastasize to distant tissues and organs along lymph nodes or blood, the most common metastatic organ is liver, followed by lung, bone and so on. The most common metastases are liver, followed by lung and bone. Progressive colon cancer may even have peritoneal implant metastases. The treatment of colorectal cancer mainly includes surgery as the main treatment, combined with radiotherapy, immunotherapy and Chinese herbal medicine. Colorectal cancer is a new organism formed by abnormal gene regulation of normal colorectal tissues under the stimulation of carcinogens and abnormal proliferation of normal tissues, which can grow locally infiltrative and can also occur local or distant metastasis, and should be treated early once detected.