Marburg virus is a filovirus, which is a fatal and virulent infectious virus. Marburg virus causes Marburg hemorrhagic fever with a mortality rate of more than 90%. The time interval from when a patient is infected with the virus to the onset of symptoms varies from 2-21 days. The incubation period of Marburg hemorrhagic fever is usually 3-9 days. The onset of Marburg virus infection is rapid, with initial discomfort such as high fever, severe headache, and muscle pain, followed by severe watery diarrhea, abdominal pain, cramps, nausea, and vomiting on the third day, and diarrheal symptoms lasting up to one week. At this stage, the patient’s appearance may appear “devil-like”, with deep-set eyes, expressionless face, and extreme drowsiness. At 5-7 days of infection, severe bleeding occurs from various parts of the body, such as the nasal cavity, gums, vagina, and blood in vomit and stool, accompanied by a persistent high fever, also known as Marburg hemorrhagic fever. The patient also has a rash all over the body, but it is not itchy. The patient has elevated transaminases, decreased lymphocytes, increased neutrophils, and significantly decreased platelets with abnormal hypercoagulability. Current investigations have shown that infections can be caused by direct contact of healthy people with blood, secretions, organs, etc. of infected persons or animals. Therefore, prevention and control of the virus is very important, especially for people in areas where Marburg virus infection has been observed, they should wear masks and gloves to avoid close contact with patients. For suspected patients or indirect contacts, infection control precautions should be taken.