For the treatment of common bile duct stones, the traditional method is to remove the gallbladder by cesarean section, open the common bile duct and place a “T” duct, which is a very traumatic procedure with many complications and a long hospital stay. In order to ensure that the stones that may remain from the surgery can be removed again, patients are often required to keep the “T” duct in place for more than two months so that a flint tract can be formed around the “T” duct and the choledochoscope can enter the common bile duct through this flint tract to remove the stones that may remain. In order to explore the minimally invasive treatment of common bile duct stones, we performed laparoscopic surgery combined with lithotripsy mesh to remove common bile duct stones in 21 patients with gallbladder stones combined with common bile duct stones, and the surgery was initially successful, making minimally invasive surgery of common bile duct stones possible. For stones larger than 1 cm, the stones can be crushed first with the lithotripsy mesh basket and then inserted into the retrieval mesh to remove the stones. For fine and quicksand-like stones, a large amount of saline can be injected from the retrieval mesh for flushing, and a certain pressure is given during flushing. Although the operation was successful in all 21 patients in this group, we believe that this method is not suitable for patients with septic cholangitis, stones larger than 2 cm, biliary pancreatitis and biliary tract in inflammatory phase. The operation of the combined laparoscopic lithotomy network for the treatment of common bile duct stones instrumentation is more complicated, in the first few cases, the operation time is long because it is in the exploration stage, after about 8-10 cases of training, the operation will be skilled and the operation time will be greatly shortened, and close cooperation of the radiologist is also required. For most of the time, the surgeon is directly exposed to X-rays. For the convenience of operation, the protective clothing cannot protect the surgeon comprehensively, which brings damage to the surgeon’s health. It is an urgent issue for the treatment of common bile duct stones by combined laparoscopic lithotripsy network to reduce the exposure time and increase the protection for the surgeon.