Antan (benzhexol hydrochloride) is a commonly used psychiatric drug, mainly for the relief of antipsychotic-induced extrapyramidal symptoms, and it is very effective. Therefore, many patients and family members, and even many psychiatrists, believe that the use of antipsychotics requires the prophylactic use of Antan, and that once Antan is used, it should be used for a long time. Is this really the case? This is actually two misconceptions about the use of Antanomics. Myth #1: Prophylactic use of Antan. Older generation antipsychotics do tend to cause extrapyramidal symptoms. Some studies have reported that 50% of patients taking older generation antipsychotics experience extrapyramidal symptoms to varying degrees. Therefore, we can well understand the feelings of patients, their families and physicians to use Antanom for preventive purposes. However, with the introduction of newer antipsychotics (e.g., olanzapine, risperidone, quetiapine, aripiprazole, ziprasidone, etc.), this situation has improved considerably. Most patients taking the newer antipsychotics do not develop extrapyramidal symptoms. Even with the older generation of antipsychotics, half of the patients do not develop extrapyramidal symptoms. Therefore, there is no need for prophylactic use of Antan. The Chinese often say that “medicine is poisonous in three parts”. Although Antan is used to counteract the side effects of antipsychotics, Antan itself has side effects. The most common side effects of Antanomics are anticholinergic effects, such as dry mouth, constipation, blurred vision, urinary retention, tachycardia, and memory impairment. In addition to this, Antanom can also reduce the blood concentration of antipsychotics and affect the therapeutic effect of antipsychotics. Some studies even suggest that Antanomics can also increase the risk of delayed-onset movement disorders. Since there are also side effects of Antanomics, we should use Antanomics with caution, avoiding prophylactic use and using it only when necessary. Myth 2: Long-term use of Antanomics. Many patients take Antanom once they use it for a long time. Patients and family members are afraid to stop using Antan because they fear that if they stop using Antan, the extravertebral system symptoms will appear again. In fact, many studies have found that if patients experience extrapyramidal symptoms after using antipsychotics, the body automatically regulates them and can usually tolerate these side effects after 1-2 weeks. In other words, patients with extrapyramidal symptoms can tolerate these reactions on their own, even if they are not taking Antanomics. It has also been found that patients taking Antan for 3 months and then changing the treatment from Antan to placebo (same appearance as Antan but no pharmacological effect) did not have a reappearance of extrapyramidal symptoms. Therefore, we have no need for long-term use of Antan. We recommend that after 3 months of Antan, the patient can gradually reduce the Antan dose or even stop using it under the guidance of a physician. If you are using Antan for prophylactic or long-term use, please re-evaluate the need for Antan with your primary care physician.