A lot of small particles near the nose are considered to be related to acne and milia. Topical medication and physical therapy can be given, and it can also be treated by surgery. 1. Acne: Hormone level changes in the body, sebaceous gland secretion increases, follicular opening is blocked, resulting in blackheads or whiteheads on the skin. It can be treated with topical azelaic acid and retinoic acid ointment. If accompanied by bacterial infection, it can be treated with topical preparations such as erythromycin ointment and chloramphenicol ointment. If acne develops into boils with more obvious symptoms, it can be drained through surgical incision if necessary and treated with anti-infection after surgery. 2. Corns: Corns are small cysts formed by the treatment of epithelial keratin of sebaceous gland ducts, which can occur near the nose, resulting in the appearance of small particles around it. If there are no symptoms, it can be closely observed. If you feel that it affects your aesthetics, you can treat it with laser ablation and electrodesiccation. If a lot of small granules appear near the nose, and if they are accompanied by obvious itching sensation, it is also important to know whether it is related to allergy, and it is recommended to visit the hospital to find the cause and treat it under the guidance of the doctor.