If the sudden onset of weakness occurs on the same side of the body and there are clear risk factors for cerebrovascular disease, such as hypertension, diabetes mellitus, dyslipidemia, or a history of cerebrovascular disease, the most likely cause is a stroke. The most common types of stroke are cerebral infarction or cerebral hemorrhage. The patient needs to go to the hospital and undergo a relevant head CT or head MRI to determine whether there is any new cerebrovascular disease. If there is sudden weakness of limbs, which is manifested as weakness of upper limbs and lower limbs, and the limbs cannot be lifted and moved, attention should also be paid to the presence of hypokalemia, which is commonly caused by poor eating, diarrhea, vomiting and pain in the clinic. Some patients are induced by hyperthyroidism and other diseases such as hypokalemic periodic paralysis, patients need to carry out relevant laboratory tests.