The painful pressure on the side of the big toe may be caused by tight shoes and prolonged extrusion, generally every redness and swelling, wearing loose shoes for 1-2 days to improve naturally. It may also be a nail fungus, which may only be locally red with no obvious swelling and pus in mild cases, or redness and pus in severe cases. For less serious nail fungus, trim the local nail in time and use anti-inflammatory drugs such as mupirocin ointment locally. In more severe cases of nail fungus, the nail should be removed and the nail bed trimmed, and antibiotics such as levofloxacin injection should be given intravenously to combat the infection. Other causes, such as bunion deformity and gout, can be determined by local x-rays and uric acid tests, and in the case of gout, colchicine can be used to reduce uric acid and magnesium sulfate can be applied topically to facilitate recovery.