There are several possible causes of joint pain at the root of the big toe: first, gout, most patients with gout have joint pain at the root of the big toe as the first symptom, often accompanied by skin redness and swelling and increased skin temperature, and in severe cases, gout stones may be formed, which requires early blood uric acid tests and relevant foot x-ray for early diagnosis and treatment; second, joint tuberculosis, when the joint at the root of the big toe has tuberculosis or When the joint at the base of the big toe has tuberculosis or soft tissue tuberculosis, there can be pain in the joint, and it can also be accompanied by skin redness, swelling and fever. If necessary, pathological examination should be performed.