Hepatitis B weak positive, if the titer of hepatitis B surface antibody is less than 10mIU/ml, it is necessary to take vaccine. Hepatitis B weak positive means that the body has some immunity to hepatitis B virus, at this time, it is necessary to receive quantitative testing of hepatitis B antibody, and according to the results of the test to analyze whether it is necessary to receive hepatitis B vaccine. If the titer is between 10-100mIU/ml, only booster shots are needed; if the titer is below about 10mIU/ml, 3 shots are needed. If the antibody titer is greater than 100mIU/ml, no vaccination is needed. The more common adverse reactions to hepatitis B vaccination are localized redness, swelling, heat and pain as well as nodular symptoms at the vaccination site. In addition, it may cause generalized fever symptoms, which can be reduced by physical cooling therapy. Hepatitis B vaccine is contraindicated, including fever, acute disease exacerbation and allergy and other symptoms can not be vaccinated. Before vaccination, it is recommended to consult a specialist to determine whether vaccination is possible and the specific vaccination plan.