Reflux esophagitis take acid inhibitors such as omeprazole, pro-gastrointestinal dynamics drugs such as mosapride, mucosal protection drug thioglycollate, etc., there are individual differences in the time of taking. 1. Acid inhibitors: proton pump inhibitors acid inhibition is stronger, is the first choice of drugs, such as omeprazole, lansoprazole, pantoprazole, etc., usually the course of treatment 4 to 8 weeks. For those with more severe conditions, the course of treatment can be extended appropriately. There are also histamine H2 receptor antagonists, such as cimetidine, ranitidine, etc., with a course of treatment of 8 to 12 weeks. However, the acid-suppressing ability is weaker than the former. 2. Gastrointestinal stimulants: promote gastric emptying, reduce gastrointestinal reflux, as an adjunctive drug and acid suppression drugs. Commonly used drugs are mosapride, domperidone and so on. 3. Mucosal protection drugs: promote the repair and healing of damaged mucosa, commonly used drugs such as aluminum sulfate. There are also antacids such as magnesium hydroxide, which can neutralize stomach acid. The drugs should be used according to the doctor’s instructions. Treatment of reflux esophagitis medication course of time due to the degree of disease, individual sensitivity to drugs and other factors, there are individual differences, need to be under the guidance of the doctor reasonable use of drugs.