Does painful stool necessarily mean anal fissure? In addition to anal fissures, severe anal pain can also be seen in the following diseases: ① Perianal abscess This disease is more common and is commonly known as “abscess”. A lump can be found next to the anus, which is painful to touch and sometimes accompanied by fever. The pain is more intense and increases with activity. If the location is shallow, it can break down on its own and pus can flow out. Internal hemorrhoids are commonly found in patients with mixed hemorrhoids, due to dry stool, long squatting time, cold, anxiety and other reasons, resulting in inflammation and edema of the mixed hemorrhoids and prolapse of the internal hemorrhoids. ③Anal rectal cancer in late stage Severe pain. Treatment: medication for pain relief, no other methods. Therefore, if you have a painful anal disease, you must go to a specialist anorectal hospital to ask a doctor to check and judge to determine which disease it is.