Pericardial effusion <200ml requires diagnostic puncture and aspiration, acute pericardial occlusion requires puncture and aspiration, and the amount of effusion >500ml requires puncture and aspiration. 1. When the pericardial effusion is less than 200ml, even if there is no symptom, diagnostic puncture and fluid aspiration is needed, and the drainage fluid will be examined by routine, biochemistry, bacterial culture and search for antacid bacilli, so as to clarify the cause of the disease, such as tumor, tuberculosis, inflammation, etc., and then treat the cause of the disease. 2. If acute pericardial occlusion occurs, such as dyspnea, shallow respiration, cyanosis, etc., and if hemodynamically stable (blood pressure > 90/60 mmHg), puncture and fluid aspiration are required for treatment and fluid aspiration for examination. If hemodynamic instability (blood pressure <90/60mmHg), it is necessary to perform contraindicated pericardiocentesis or pericardiocentesis to drain the pericardium, and at the same time to provide rehydration and elevation of blood pressure treatment. 3. When the volume of pericardial effusion is >500 ml, in addition to diagnostic fluid extraction, puncture and fluid extraction treatment is also required. If pericardial effusion occurs, it is necessary to consult the doctor in time to identify the cause of the disease and provide targeted treatment.