Gonorrhea is a sexually transmitted disease (STD) caused by gram-negative diplococcal infection, or gonococcal infection. After an incubation period of 3-5 days following sexual misconduct, yellowish-green pus appears at the site of contact accompanied by a tingling sensation. At this time, a smear and culture of the secretion can detect gram-negative diplococci, and the culture can detect gonococci. At this time need to give regular treatment, men can be given Spectinomycin 2.0g intramuscular injection once, women need to be given Spectinomycin 4.0g intramuscular injection once. Both sex partners are required to have a joint examination and treatment, avoiding sexual contact during treatment to avoid cross-infection, and regular review after treatment.