Autologous fat augmentation of the base of the nose is to fill up the base of the nose by filling up autologous fat to improve the feeling of facial depression and make the face look more three-dimensional, and at the same time, it can also reduce the decree lines to a certain extent. Although this procedure is more commonly used in clinical practice, there are still certain surgical risks, as follows: 1, fat calcification is more common and serious sequelae after autologous fat filling, mostly due to excessive one-time dosage of fat or injection is too centralized, a large amount of fat is piled up together, and the adipose tissue can not produce a good blood supply, which in turn leads to fat necrosis; 2, surgical contusion of subcutaneous tissues caused by a lot of Can lead to hematoma, generally can subside by itself; 3, patients in 1-3 months after the operation, may occur pigmentation, grafting too much or not enough, etc., need to closely observe the condition, in order to avoid serious situations; 4, fat-filling process, the medical practitioner aseptic operation is not standardized, or the patient’s resistance to decline after the operation can lead to infection, the skin localization of redness, swelling, heat and pain, etc.; 5, injection of fat into blood vessels, can lead to fat necrosis; 5, injection of fat into blood vessels, can lead to fat necrosis; 6, fat injection of fat tissue can lead to fat necrosis. Injecting fat into blood vessels can cause vascular embolism, and in serious cases, blockage of the ophthalmic artery, which can lead to blindness.