Hepatitis B 3-in-1 vaccine, which refers to the hepatitis B vaccine containing 60μg each, is much more expensive than the 10μg or 20μg hepatitis B vaccine, and can generally reach a price of about 300 RMB, but this is just as a reference, its price will fluctuate in different areas, at different times, in different hospitals or vaccination stations, and some vaccination stations do not even have 60μg of Hepatitis B vaccine, so you should consult your local vaccination agency to know the price. For the 10μg or 20μg hepatitis B vaccine, the first complete injection requires three doses to achieve immunity, while if the 60μg triple hepatitis B vaccine is applied, it is likely that immunity will be achieved with one dose. In addition, there are some people who still do not produce hepatitis B surface antibodies after three doses of hepatitis B vaccine. These people belong to the category of low or no immune response, and this kind of people are more suitable to apply the 60μg hepatitis B vaccine because it is a higher dose, so it is likely to produce hepatitis B surface antibodies after one injection.