Signs of the day before death in patients with chronic obstructive pulmonary disease may include, altered mental status, extreme dyspnea, severe edema, and excessive sputum. 1. Altered mental state, often manifested as drowsiness, lethargy, coma, or mental behavioral abnormalities, such as gibberish, apathy, hyperactivity, with searching for clothes and touching the bed, and so on. 2. Extreme respiratory distress, open-mouth breathing, sigh-like breathing, hypoxemia and hypercapnia, often suggesting imminent death. 3. Severe edema, mainly in the low-hanging parts of the body, such as the lower limbs, and even abdominal fluid, pericardial effusion, which suggests that the patient’s cardiopulmonary failure. 4. The sputum is thick and sticky, not easy to cough up, which can easily lead to sputum blockage and suffocation. The above is for reference only, patients with chronic obstructive pulmonary disease need to consult a doctor in time.