Nausea and vomiting in the middle of the headache may be caused by physiological factors, meningitis and upper respiratory tract infections, intracranial space-occupying lesions and other factors, the patient can pay attention to rest and according to the cause of the doctor’s instructions to use ganciclovir, ceftazidime, and aspirin, acetaminophen and other medications to carry out treatment. 1. Physiological factors: if the patient is overworked, lack of sleep, there may be a headache in the middle of the nausea and vomiting symptoms, generally do not need special treatment, pay attention to rest. 2. Meningitis: headache, nausea and vomiting are the main characteristics of meningitis patients. However, due to the different causes of the disease, there will be differences in the use of drugs, such as viral meningitis can use antiviral drugs such as ganciclovir, septic meningitis can use antibiotics such as ceftazidime. 3. Upper respiratory tract infections: these patients also usually appear in the middle of the headache nausea and vomiting symptoms, patients can follow the doctor’s instructions to take non-steroidal anti-inflammatory drugs aspirin, acetaminophen and other drugs for treatment. 4. Intracranial space-occupying lesions: such as cerebral hemorrhage, brain tumors. It can cause increased intracranial pressure leading to headache, vomiting and other symptoms. The effect of oral drug treatment is not good, usually take surgical treatment. Causes of headache nausea and vomiting in the middle of the reason is more, it is recommended that patients go to the hospital in time for examination, clear causes, targeted treatment, strictly comply with the doctor’s instructions for the use of drugs.