In iron deficiency anemia, there is a decrease in white blood cells, which is usually harmful because it leads to an increased risk of infection. If the diagnosis of simple iron deficiency anemia is confirmed by examination, a mild leukopenia is a common manifestation, as well as a mild elevation of platelets. Generally, the risk of infection is increased with leukopenia, but no specific treatment is necessary for mildly decreased white blood cells, which can be restored with correction of the iron deficiency anemia. If the iron deficiency anemia is combined by other diseases, such as paroxysmal sleep hemoglobinuria, systemic lupus erythematosus, etc., in this case, the leukopenia is more or less caused by the primary disease, then it is necessary to treat the primary disease before the white blood cells can be restored. When iron deficiency anemia anemia, accompanied by low white blood cells, it is recommended to ask the doctor in time to clarify the cause of the disease, and then receive standardized treatment.