The normal range of total bile acids is 0-9.67μmol/L (fasting), if the test result is 20μmol/L, it is a high situation, the specific reasons are as follows: 1, physiological: such as after eating serum bile acids can be transiently elevated; 2, liver cell damage: such as acute hepatitis, chronic hepatitis moderate, liver cirrhosis, fatty liver, liver cancer and toxic liver disease and other liver diseases, the more serious liver function damage 3, biliary stasis: such as intrahepatic and extrahepatic bile duct obstruction, can also increase the level of total serum bile acids; 4, portal shunt: secondary bile acids in the intestine, through the shunted portal system, directly into the body circulation, can be manifested as an increase in the level of total serum bile acids; 5, the early stage of drug toxic hepatitis: when there are no obvious clinical symptoms, can also be manifested as an increase in the level of serum bile acids 6, intestinal reabsorption of bile acids and hyperthyroidism: enhanced synthesis of bile acids, often accompanied by a decrease in blood cholesterol; 7, hyperlipoproteinemia: disorders of bile acid metabolism can occur. Elevated fasting serum bile acids can reflect substantial liver damage, but they also need to be combined with other liver function tests to further confirm the cause and provide a reliable basis for clinical diagnosis.