The cure rate of advanced lung cancer is almost 0. Clinically, lung cancer is divided into central lung cancer and peripheral lung cancer, which can be classified into non-small cell lung cancer and small cell lung cancer according to cytological classification. However, if the lung cancer is caused by adenocarcinoma with positive gene mutation, chemotherapy and gene targeting therapy can significantly extend the survival period to more than 2 years or even less than 10 years. There is not much hope to cure advanced lung cancer, but according to the basic condition of the patient, especially the cytological classification and gene targeting test, the survival period can be extended appropriately. It is not necessary to be completely pessimistic in advanced lung cancer stage, and it is necessary to actively formulate reasonable treatment plan to prolong the survival period and improve the quality of survival according to the suggestions and opinions of doctors.