The cause of numbness at the tip of the tongue may be peripheral nerve injury, cerebrovascular disease and so on, which can be treated with medication, but the appropriate treatment should be chosen according to the cause of the disease. 1. Peripheral nerve injury: it may be caused by bacteria, viral infection, diabetes and other reasons. Bacterial infection can be treated with antibiotics such as penicillin, cephalosporin and other broad-spectrum antibiotics; viral infection can be treated with antiviral drugs such as acyclovir; diabetes can be treated with insulin, metformin and other medications; treat the primary disease first, and use painkillers jointly if necessary. 2. Cerebrovascular disease: cerebrovascular disease can lead to trigeminal nerve injury, often due to atherosclerosis, blood viscosity increased, can be based on the treatment of cerebrovascular disease by adjusting the lifestyle to alleviate the problem, such as appropriate exercise, improve the dietary structure such as reducing the intake of fatty foods, increase the intake of vegetables and fruits, and avoid staying up too late and so on. There are other reasons for the numbness of the tip of the tongue, it is recommended to consult a doctor for diagnosis and treatment.