Acromegaly, also known as amyotrophic lateral sclerosis, is one of the most common types of motor neuron disease. Motor neuron disease is a degenerative disease that slowly progresses and worsens since its onset, with a chronic progressive exacerbation. The rate of progression of acromegaly varies from patient to patient. Clinically, there are patients with rapid progression who develop respiratory muscle paralysis in about 1 year, and clinically, there are patients who develop respiratory muscle paralysis after 4-5 years. For the speed of progression of acromegaly, it is about 3-5 years before the patient develops respiratory failure and requires a ventilator to assist with breathing. For people with acromegaly, the average age of survival will also be within 3-5 years, with individual patients reaching 5-10 years. Progression of acromegaly is relatively fast for other chronic diseases.