Redness and fever after taking antihypertensive drugs should be considered to be caused by the side effects of antihypertensive drugs. The most common antihypertensive drugs that cause flushing and fever are calcium channel blockers, such as nifedipine controlled release tablets, lacidipine, amlodipine and so on. If a patient is taking antihypertensive medications that cause flushing and fever, there is no need to adjust the medication if the symptoms are not severe. If the flushing and fever cause obvious discomfort, even affecting work and sleep, other first-line antihypertensive drugs can be adjusted for antihypertensive treatment. In the clinical treatment of hypertension patients with antihypertensive therapy, need to be based on the patient’s specific situation to give individualized treatment, any drug has certain side effects, to choose suitable for the patient’s antihypertensive drugs, so that the patient’s blood pressure can be controlled for a long time.