Vulvar hpv53 positive indicates that the patient has human papillomavirus infection, may cause abnormal leukorrhea. Vulvar hpv53 positive patients may cause warts, cervical pre-cancerous lesions and other diseases, different situations patients will have different symptoms: 1. acromegaly: for patients diagnosed with acromegaly, patients tend to have localized light red papules, and with the development of the disease, localized cauliflower-like or papilla-like cumbersome organisms will appear, accompanied by pain or contact bleeding. 2. cervical precancerous lesions: women infected with hpv53 without intervention, with the passage of time is likely to lead to local precancerous lesions, this time the patient will appear abnormal leukorrhea, bleeding after intercourse, abdominal pain and other discomforts. For vulvar hpv53 positive patients, may appear abnormal leukorrhea, so it is recommended that patients to regular hospital gynecology consultation, if necessary, perfect colposcopy and other related examinations, under the guidance of the doctor active treatment.