The first thing to consider is whether there is a foreign body piercing into the skin of the nail seam, and you should carefully check whether there is a foreign body in the painful area of the nail seam. If there is a foreign body, it should be removed in time and treated against infection, otherwise it will lead to periungual inflammation and other diseases. If it is stabbed by an iron sharp object, the patient should immediately go to the hospital for a tetanus injection to avoid infection by the tetanus bacillus. Nail seam pain can also be skin allergies or skin infections, inflammatory reactions, if the allergic reaction to stay away from allergens, serious cases can be applied to anti-allergy drugs, infected patients with anti-bacterial or anti-fungal drugs. In addition, the pain may be caused by nail cracking, mostly due to malnutrition or external stimulation. This situation should prevent the wound from infection and suppuration, and due to the special characteristics of the site, the wound is not easy to heal, the patient must do a good job of wound care.