Most of the kidney diseases are a group of immune diseases. Long-term proteinuria as well as immunosuppressant treatments make kidney patients with low immune function and weakened ability to resist external evils. Although chronic kidney disease patients are most avoided to suffer from colds, as a result, they are most prone to colds. Influence of cold on kidney disease Kidney disease patients with secondary cold or other chronic infections have the following effects on the body: 1. Trigger the recurrence of kidney disease After the cold virus infects the human body, the body produces antibodies, which combine into immune complexes. This can eliminate foreign antigens (bacteria or viruses), but the formation of immune complexes will also be deposited into the renal tissue, leading to inflammatory cell infiltration, inducing inflammatory response, thus causing nephritis. Therefore, patients with kidney disease often have attacks of hematuria and increase of proteinuria after cold. 2, aggravate the condition During cold and flu, the body’s metabolism is hyperactive, metabolic products and a large number of harmful inflammatory mediators increase, these substances not only aggravate the excretory load of the kidneys, but also may stimulate local inflammatory response, accelerate the progression of renal tissue lesions. Many patients not only aggravate proteinuria after the cold, but also deterioration of renal function. 3, combined medication renal damage Many people in the cold regardless of the cause of the cold, the first service antibiotics and then hang water, their own toss some, the results of the cold is not controlled also caused by the rapid deterioration of renal function. In fact, the vast majority of colds are caused by viruses, and antibiotic treatment has nothing to do with it. Many antibiotic drugs need to be excreted by the kidneys, and there is a possibility that kidney damage may be induced in the process of medication. Even drugs that have been used in the past and are considered safe may cause kidney damage in febrile and dehydrated states. Therefore, it is important not to abuse antibiotics and other drugs that may harm the kidneys, especially intravenous fluids, without a clear indication.