The significance of thyrotropin receptor antibody test is to understand the cause of hyperthyroidism, treatment and recurrence of Graves’ disease. 1. Understanding the cause of hyperthyroidism: If the patient is positive for thyrotropin receptor antibodies, it suggests that the patient’s hyperthyroidism is due to autoimmunity rather than toxic nodular goiter, and that he or she needs to be actively treated. 2. Understanding the treatment of thyroid disease: Detecting the treatment and recurrence of Graves’ disease has an important role in guiding clinical treatment and monitoring. Measurement of thyroid-stimulating hormone antibodies during pregnancy in patients with a history of thyroid disease is important to assess the risk of thyroid disease in the newborn. If the result is positive, the patient should be treated aggressively and have regular thyrotropin receptor antibody tests to see how the body is recovering and to prepare for subsequent treatment.