The common causes of itching inside the penis include gonococcal urethritis, nongonococcal urethritis, condyloma acuminatum, and acute prostatitis. 1. Gonococcal urethritis: usually manifested as itching and tingling symptoms in the penis, urine or secretions for smear or culture can be found gonococcus, can follow the doctor’s instructions to use ceftriaxone sodium intravenous infusion treatment. 2. non-gonococcal urethritis: attribute transmission disease, usually mycoplasma, chlamydia infection, itching and burning sensation in the penis, accompanied by frequent urination, urinary urgency, urinary pain and so on. The urine or secretions are smeared or cultured for a clear diagnosis, and macrolide antibiotics such as azithromycin or erythromycin can be used to treat the condition, and sexual partners need to be co-treated. 3. Warts: a sexually transmitted disease, usually caused by infection with human papilloma virus, at first localized reddish papules, with the symptoms of aggravation will appear to increase the phenomenon, most of the vegetable pattern protruding, the penis will be itchy, as well as a sense of foreign body, pressure feeling. The actual fact is that it is not a good idea to have a local excision to do a pathology examination, and after the diagnosis is clear, antiviral treatment is needed. 4. Acute prostatitis: Systemic symptoms include high fever and chills, while local symptoms include pain in the suprapubic area and perineum, lower abdominal swelling, and itching in the penis. The prostate fluid routine, urine routine and other tests need to be done in order to make a clear diagnosis. The symptoms of itching inside the penis, it is recommended to consult a doctor in a timely manner, to clarify the cause of the disease, under the guidance of the doctor to choose the appropriate treatment program for the cause, avoid self-medication, so as not to delay the condition.