Because Crohn’s disease is a disease with complex and diverse clinical manifestations, and many physicians in China do not know enough about this disease (mainly because the disease is relatively rare and non-specialists do not have enough experience), many physicians suspect that patients have Crohn’s disease, such as colon ulcers found by colonoscopy or anal fistulas in young patients, but many non-specialists do not have enough experience, so this time the patient needs to find However, many non-specialists are not experienced enough, so it is necessary to find a specialist to further confirm the diagnosis. If Crohn’s disease is suspected, how should a patient seek further medical advice? First, find a specialist in a major hospital, for example, several major hospitals in Hangzhou have special clinics. For example, several large hospitals in Hangzhou have special clinics. ZJYZE and ZZE have special clinics for inflammatory bowel disease (IBD, including ulcerative colitis and Crohn’s disease). You can find out the clinic hours online (IBD clinic at ZJII is Tuesday afternoon, Dr. Wang Xiaoying, deputy chief physician, and Thursday morning, Dr. Chen Yan, chief physician, can come to the clinic and add numbers directly.) These IBD specialist clinics are seen by specialist physicians and can provide standardized diagnosis and treatment of your disease. Please note that you should not blindly believe in some non-public hospitals searched on X-do (and these hospitals are often under the guise of high profile), there have been many patients who have been fooled! Next, proceed to the next step of examination. This is more involved, and generally patients suspected of Crohn’s disease will need to undergo a full gastrointestinal examination. That is, you will need a full gastroscopy, colonoscopy, and small bowel exam. The first two are easier, but the small intestine examination is more problematic because the small intestine is in the middle of the stomach and large intestine and is very long (generally considered to be 4 – 6 meters), and a full endoscopic look is very difficult. All, for most patients, the physician will recommend that you first undergo a small intestine CT or small intestine MRI (especially for younger patients try to use MRI to to reduce radiation), and then consider whether to do capsule endoscopy or small bowel microscopy as the next step, if appropriate. It is also important to evaluate the anal region, and your physician will take the next step based on your medical history (e.g., any previous fistulas, fissures, etc.). These tests are sometimes really torturous, but they are very important, and early diagnosis is extremely valuable for treatment, so we hope you understand and cooperate. Then, a pathology consultation of the endoscopic biopsy specimen is required. Pathology is very important, but in Crohn’s disease it is difficult and not always endoscopic biopsies can reveal characteristic features, so often it is difficult to confirm the diagnosis and the clinician needs to evaluate it in conjunction with other tests. Sometimes, a positive blood test (e.g., serum antibodies against Saccharomyces cerevisiae) can be valuable for diagnosis, but a negative blood test does not necessarily mean that you do not have Crohn’s disease, as the sensitivity of such tests is low. Because Crohn’s disease has a complex clinical presentation and a relative lack of a specific index for diagnosis, physicians must use a variety of tests to get a full picture of the extent and degree of disease involvement and to determine whether you can be diagnosed with Crohn’s disease based on these tests. In many cases, despite these tests, the diagnosis may still be clinically suspect! We hope you understand. Although the diagnosis is doubtful, your physician will need to treat you promptly and follow up with you, and in many cases Crohn’s disease will be diagnosed later during follow-up visits. In short, if you are suspected of having Crohn’s disease, please do not panic, first find a specialist, have a thorough examination, then discuss with your physician an appropriate plan based on the results of the examination, and if the diagnosis is not confirmed, make sure to follow up!