Metformin extended-release tablets are generally recommended to be taken with or after meals to minimize gastrointestinal irritation due to gastrointestinal side effects. Metformin extended-release tablets are hypoglycemic drugs that are white to off-white tablets or film-coated tablets. It is mainly used for the treatment of type 2 diabetes mellitus that cannot be well controlled with diet and exercise therapy alone. This product can be used alone or in combination with sulfonylureas or insulin. Adverse reactions to taking this product are commonly gastrointestinal symptoms such as nausea, vomiting, acid reflux, and abdominal pain. Contraindications to the drug include type 2 diabetes combined with acute severe metabolic disorders, severe infections, hypoxia, trauma, major surgery, pregnant and lactating women, etc.; those who are allergic to the drug or have had a serious adverse reaction to it; and alcoholics. You need to consult your doctor before taking metformin extended-release tablets to avoid taking the drug on your own, which may cause adverse consequences.