Chest wall pain needs to be treated according to the specific causes, which include lung and mediastinal lesions, chest wall diseases, cardiovascular diseases, etc. After diagnosis, general treatment, medication and surgery are chosen. 1. Lung and mediastinal lesions: diseases such as pneumonia, pneumothorax and pleurisy can cause chest wall pain. It can be treated with anti-infection drugs, such as cefdinir and penicillin. If it is diagnosed as lung cancer, it needs to be treated by surgery, with chemotherapy and radiotherapy after surgery. If it belongs to pneumothorax, thoracentesis and aspiration surgery is needed. 2. Chest wall diseases: pleurisy, rib fracture, intercostal neuralgia and other diseases can cause chest wall pain. Treatment needs to be based on anti-infection, pain relief, and nutritive nerve therapy, such as cefdinir, acetaminophen, and methylcobalamin. If it is a serious fracture, it needs to take surgical treatment. 3. Cardiovascular disease: angina pectoris caused by coronary heart disease will cause myocardial ischemia, resulting in chest wall pain. Nitroglycerin can be used for treatment, and if the blood vessel blockage is serious, interventional therapy or open chest surgery can be taken. There are many reasons for chest wall pain, after the symptoms, we suggest that we go to the hospital in a timely manner, follow the doctor’s instructions to take standardized treatment, the above drugs should be used under the guidance of a doctor, and should not be used indiscriminately, so as not to lead to adverse consequences.