In mild dichlorvos poisoning, plasma exchange can basically return to normal. If dichlorvos severe poisoning, may cause lower limb paralysis, muscle atrophy and other neurological sequelae, at this time plasma replacement may not return to normal. Dichlorvos poisoning belongs to the organophosphorus pesticide poisoning, mild poisoning, inhalation is less, less damage to the mucous membrane, the toxic reaction is generally mainly gastrointestinal irritation, usually not through the mucous membrane diffusion of the whole body, and timely gastric lavage and plasma replacement and other treatments will not generally leave sequelae. If the patient inhaled a large number of dichlorvos leading to severe poisoning, a large concentration of dichlorvos will quickly stimulate the damage to the gastrointestinal mucosa, mucosal damage after the drug can be absorbed through the mucous membrane diffusion to the whole body, and in severe cases, the nervous system will be involved, so that paralysis, muscle atrophy and other sequelae. In summary, the patient dichlorvos poisoning plasma replacement can be normal with the patient’s degree of poisoning, it is recommended that the patient is poisoned in a timely manner to seek medical treatment, the specific results to the doctor shall prevail.