Redness, swelling and pain in the buttocks may be caused by localized folliculitis, sinusitis, perianal abscess and other diseases, which can be combined with the cause of conservative treatment or surgical treatment. 1. Folliculitis: if the anus long folliculitis, not timely treatment, folliculitis gradually increase will repeatedly stimulate the local, easy to lead to local redness, swelling, pain. Erythromycin ointment, mupirocin ointment, fusidic acid ointment can be applied externally. If a larger boil is formed locally, local drainage can be carried out. 2. Sinusitis: mainly due to the acute reaction caused by infection and inflammation, stimulated by inflammation, will lead to redness, swelling and pain around the buttocks and anus. At present, the main anti-infective and symptomatic treatment as the principle, you can use water to clean the local, and then apply erythromycin ointment, if necessary, oral metronidazole. If the condition is more serious, the need for anal sinus incision and drainage. 3. Perianal abscess: mainly due to the anus repeatedly stimulated by the outside world or inflammation, when the formation of perianal swelling will cause pain. It is recommended to perform abscess incision and drainage as soon as possible, and then apply erythromycin ointment externally after the operation. Red, swollen and painful buttocks may also be caused by hemorrhoids, anal fissure and other diseases, the cause of which should be analyzed before treatment and carried out in strict compliance with medical advice.