Elevated neuron-specific enolase can be seen in certain neuroendocrine tumors, cerebrovascular diseases, craniocerebral trauma, etc., and can be consulted in the corresponding surgical department or oncology department, department of neurology, department of neurosurgery. Elevated neuron-specific enolase is mostly seen in neuroendocrine tumors, for example, small cell lung cancer can be consulted in thoracic surgery; neuroblastoma can be consulted in neurosurgery; medullary thyroid carcinoma can be consulted in thyroid and breast surgery, and so on. The malignant tumors mentioned above can also be seen in the Department of Oncology. Elevated neuron-specific enolase can also be seen in various craniocerebral injury diseases, such as traumatic brain injury, cerebral hemorrhage, cerebral infarction, etc. Depending on the condition of the patient, he/she can choose to go to the neurosurgery department or the neurology department for consultation. Patients with elevated neuron-specific enolase are advised to go to the hospital as soon as possible for prompt identification of the cause and early treatment.