Brucellosis can be treated with drugs such as doxycycline, rifampicin and cotrimoxazole. Also, combination of ceftriaxone and levofloxacin can be used to treat severe brucellosis. Medications should be used under the supervision of a physician. When the disease is in the acute stage, doxycycline combined with rifampicin or doxycycline combined with streptomycin may be preferred for treatment. If the above medications are not available or are not effective, doxycycline in combination with cotrimoxazole or rifampin in combination with a fluoroquinolone may be used. In addition, combination of ceftriaxone and levofloxacin can also be used to treat severe cases of brucellosis. For special populations, such as pregnant women, rifampicin combined with cotrimoxazole can be used for treatment, due to the specificity of the drug, it needs to be weighed against the pros and cons of using it before proceeding with drug therapy. When patients have comorbidities, generally can consider the application of triple or more than three drug treatment, and need to extend the course of treatment appropriately. For chronic infections, the treatment is relatively complex, then need to be based on the pathogen treatment needs to be desensitized and to deal with the potential complications of treatment. Since the drugs have certain contraindications and adverse reactions, it is necessary to consult a doctor for advice before using the drugs.
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