Not interested in anything could be the following diseases: 1, the problem of depression, depression can easily cause a decline in interest, can also cause depressed mood, happy not to get up, previously interested in things are now not interested in, and do not want to do, mental fatigue easily, and even pessimistic, negative, all day long to tears, etc.. If you have similar problems, it is likely to be depression.2. It is common in schizophrenia, especially in some long-term schizophrenic patients who have now declined, or even have negative symptoms as the main manifestation, they may be emotionally indifferent, not interested in anything, not willing to meet people, not willing to talk, etc.3. It may also be autism, some of these problems may be more common for childhood This is because these children with autism may have narrow interests, may not be interested in anything, and may have low intellectual development and some impairment and deficits in speech. Regardless of the problem or disorder, it is important to be proactive in treatment.