Increased stiffness of the peripheral arteries is usually due to thickening of the arterial walls and the development of sclerosis or plaque in the arterial walls. The underlying causes of this condition are smoking, hypertension, hyperlipidemia, hyperglycemia, and obesity, which cause the process of atherosclerosis, resulting in increased stiffness of the peripheral arteries. The appearance of this condition often reminds people to carry out prevention of related diseases to avoid atherosclerosis, which further develops leading to narrowing and occlusion of the vascular lumen and more serious clinical consequences. Therefore, the above triggers should be actively and strictly controlled, while adhering to a healthy diet and physical exercise, which is the only way to keep the process of atherosclerosis from changing and causing clinical symptoms.