There is no clear clinical data to indicate that urethane is effective when taken with what medicines, and patients need to strictly follow the doctor’s instructions for the use of medication. The main ingredients are astragalus, bitter ginseng, rhubarb, Sang Bai Pi, Atractylodes macrocephala, Poria, Paeonia lactiflora, Prepared Polygonum multiflorum, Salviae Miltiorrhizae, Plantago ovata, etc. It has the effect of strengthening the spleen, promoting dampness, lowering turbidities in the internal organs, activating the blood and removing stagnation of blood (promoting the operation of the blood to eliminate stagnation of the blood in the body). The drug is mainly used in the treatment of chronic renal failure, but also used in azotemia and early uremia, can also be used for spleen deficiency and dampness and spleen deficiency and blood stasis, and also has a certain effect on improving blood calcium, improve renal anemia and reduce blood phosphorus. However, there is no data to indicate that urethane is effective when taken with what medicines. Generally, it can be combined with antibiotics, diuretics, chemical antihypertensive drugs, uric acid-lowering drugs and other drugs that do not cause damage to renal injury, and it can be avoided in combination with adsorbents such as oxidized starch. Patients need to be under the guidance of the doctor according to the symptoms of reasonable use of drugs, and also need to be based on the degree of renal failure, a reasonable combination of diet, avoid legumes. At the same time, patients may have semi-paste stools after taking the drug, which is a normal phenomenon, and if watery stools occur, it is necessary to reduce the amount of food. It is recommended that patients take urethane under the guidance of a doctor, and if necessary, can follow the doctor’s instructions to combine medication.