The acute phase of HIV only lasts for about 1-3 weeks and then resolves on its own. Most people with acute HIV symptoms occur about 2-4 weeks after the initial HIV infection, mainly due to the presence of HIV viremia in the patient’s body, which causes damage to the immune system. Most people have fever, headache, general malaise, nausea, vomiting, diarrhea, muscle aches, rash, and swollen lymph nodes. During this period, HIV-RNA and P24 antigen can be detected in the patient’s serum, and blood can be drawn to determine whether the patient is infected with HIV. Once HIV infection is confirmed, the patient should be treated with antiviral drugs as soon as possible, even in the acute stage, to avoid the patient entering the AIDS stage.