Multiple cerebral infarction softening foci, a part of the patients can be without any clinical signs and symptoms, generally do not need special treatment, mainly given long-term secondary prevention to prevent the occurrence of reinfarction. The main clinical drugs, including long-term oral aspirin anti-platelet aggregation, oral statins such as simvastatin, resuvastatin and atorvastatin to regulate lipids and stabilize plaque. At the same time, control of risk factors, such as hypertension, patients can take oral levamlodipine or amlodipine benzenesulfonate to regulate blood pressure; patients with diabetes are generally preferred to oral metformin and bayerisepine blood pressure lowering treatment. If the effect is not good, subcutaneous insulin can also be injected to control blood glucose, so that blood glucose control at about 6mmol / L is preferred. A part of patients may develop vascular dementia, patients mainly manifested as memory impairment and intellectual disability, clinical application of the general improvement of brain metabolism treatment, commonly used drugs including olaxetan, piracetam and cytarabine, etc..