Charcot’s triad, mainly refers to the patient’s fever, chills, as well as abdominal pain and jaundice following a biliary tract infection or cholangitis and acute obstruction or purulent cholangitis. In this case, the patient is usually considered to have biliary inflammation or biliary obstruction. The patient may have yellow staining of the skin and sclera, and the patient’s liver function may indicate a total bilirubin of 34.2 umol/L or higher. If direct bilirubin is mainly elevated, combined with alkaline phosphatase and GGT elevation, the patient is usually considered to have biliary obstruction, most often due to biliary stones. In this case, patients should actively consider decompression therapy, including PTCD or PTGD for external drainage, or ERCP for stone removal and nasobiliary duct for drainage. After decreasing the biliary pressure, active anti-inflammatory treatment with cephalosporin and tinidazole is required. For some patients who have developed infectious shock, intravenous infusion of Tylenol and other drugs may be considered for anti-inflammatory treatment. Patients also need to actively consider hepatoprotective therapy and acid suppression therapy, and intravenous replenishment of fluid and electrolytes to prevent the possibility of water-electrolyte disorders.