Peeling skin in the lip area requires careful observation of the clinical signs of the broken skin area. If the peeling is purely dominated by white flakes that do not hurt or itch, consider a simple exfoliative labyrinthitis with a long treatment cycle and prone to recurrence, suggesting the option of cryotherapy and topical application of immunomodulators such as tacrolimus ointment. If the peeling area is accompanied by pain, consider irritation change, formed after contact with external substances leading to epidermal defect, consider contact with acidic substances, or possibly contact with alkaline liquid, you can apply hydrocortisone butyrate cream locally twice a day, which can effectively relieve the symptoms. If the lip peeling area with blisters, consider the perioral herpes simplex disease caused by herpes simplex type 1 virus infection, it is recommended to choose oral treatment with valacyclovir hydrochloride.