Toothache can be seen in dental disease, periodontal disease or cardiogenic toothache and other conditions, specific need to be based on clinical symptoms and laboratory tests to confirm the diagnosis. 1. Dental disease: toothache may be deep caries, pulpitis or apical periodontitis, clinical examination may find that the teeth have deep caries cavities that can reach the pulp cavity, occlusal pain, temperature or electrical vitality test abnormalities. 2. Periodontal disease: toothache may also be gingival papilla inflammation, prolonged food impaction or external material stimulation, causing gingival papilla congestion and swelling, teeth may have different degrees of spontaneous pain. Clinical examination can generally see the food stuffed in the gap between the teeth. 3. Cardiogenic toothache: cardiac system diseases such as angina pectoris can cause dental pain, often occurring after strenuous exercise, can be accompanied by associated pain, oral examination generally do not see dental disease. Electrocardiogram is abnormal. Toothache can be caused by a variety of reasons, it is recommended to go to the hospital in a timely manner to check the cause of the disease after targeted treatment.