Hepatitis B vaccine refers to recombinant hepatitis B vaccine. Moderate exercise is generally allowed after recombinant hepatitis B vaccine, but not strenuous exercise. The recombinant hepatitis B vaccine can stimulate the body to produce protective antibodies to prevent hepatitis B virus infection. Usually people in need of recombinant hepatitis B vaccine can exercise moderately after vaccination, but they should pay attention to the intensity and time of exercise, avoiding strenuous exercise and overwork, so as not to cause redness and swelling at the injection site, and even affecting the efficacy of the vaccine. Usually, recombinant hepatitis B vaccine requires 3 times of vaccination for the population. After vaccination, adverse reactions such as pain, redness, swelling, hardness and transient fever at the vaccination site may occur, which can be relieved on their own without special treatment. Hepatitis B vaccination is contraindicated in special groups such as those who are allergic to vaccine components, those suffering from acute diseases, those suffering from severe chronic diseases, pregnant women and those with uncontrolled epilepsy. It is recommended that people who have received recombinant hepatitis B vaccine should take rest, do not exercise strenuously, and should strengthen the skin care of the vaccination site to avoid the stimulation of foreign objects. If there is any discomfort after proper exercise, they should consult a doctor in time.